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PMID: 118 ZhuHWangJMiaoJShenMWangHHuangXet al

The two most popular ones are Can-C and Cineraria Maritima

The needle punctures dermal and subcutaneous tissue, triggering immediate localized trauma and mast cell degranulation

This review integrates mechanistic insights and translational findings, highlighting the promise of these natural compounds as adjunctive strategies in depression management