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Surprisingly, IF animals also presented an increase in oxidative damage in the brain that was not related to changes in mitochondrial bioenergetics

Internal structures of the head, such as the falx cerebri and tentorium, influence how the brain moves within the skull and may cause local brain regions with very high deformations only in certain directions of head rotation, so that sagittal and coronal rotations may produce more severe injuries in primates at lower accelerations and velocities (Gennarelli et al., 1982)