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This hyper-proliferative state drains the body's metabolic energy and drives the profound fatigue seen in these conditions

The concentrations were measured using Tunable Resistive Pulse Sensing (TRPS) from Izon Sciences

Ca 2+ is a master regulator of eryptosis, mediating the Gardos effect-associated RBC dehydration and reduction of cell volume (cell shrinkage), calpain activation-mediated cytoskeleton remodeling (membrane blebbing), and PS externalization, which are major hallmarks of eryptosis

doi: 10.1155/2020/8547960 [DOI] [PMC free article] [PubMed] [Google Scholar] 13.Dilokthornsakul W, Dhippayom T, Dilokthornsakul P