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The mitochondrial heat shock proteins belonging to the chaperonin family, Hspd1 (Hsp60) and Hspe1 (Hsp10), both promote the proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix 38

The cell cycle proteins S-phase kinase-associated protein-2 (Skp2) and Cyclin B1 are ubiquitinated and degraded by the E3 ligase APC/C

10.1371/journal.pone.0053096 166 TsengC

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