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Research is mixed, and supplementing with DHEA can be risky,7 but some studies suggest potential short-term, minor benefits (like improved feelings of well-being) in certain populations, such as older women with reduced natural DHEA levels.8 Ultimately, more research is needed before it can be said if DHEA supplementation is safe, particularly in the long term

doi: 10.1210/er.2013-1071 78 FrystykJIvarsenPSkjaerbaekCFlyvbjergAPedersenEBOrskovH

Preclinical Studies Early preclinical studies in rodent obesity models demonstrated that AOD9604 administration reduced body weight and fat mass without affecting food intake, indicating a direct metabolic effect rather than an appetite-suppressing mechanism

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