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Glutathione Turnover Is Increased during the Acute Phase of Sepsis in Rats

CP 200 mg/kg caused hepatotoxicity due to oxidative stress, inflammation, apoptosis, and fibrosis as manifested by a reduction in catalase, reduced glutathione (GSH), superoxide dismutase (SOD), and an increase in thiobarbituric acid reactive substance (TBARS), nitrite, tumor necrosis factor-alpha (TNF-), interleukin-6 (IL-6), transforming growth factor-beta 1 (TGF-1), interleukin-1 (IL-1), alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma-glutamyl transferase (GGT) levels

Rong H, et al

Targeting the tumor-draining lymph node with adjuvanted nanoparticles reshapes the anti-tumor immune response