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FJG, HW, GQW, AJQ and YW designed the experiments

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Participants receiving the highest dose (20 mg weekly) achieved an average body weight reduction of 22% over 36 weeks, while lower doses (1.25 mg and 5 mg) resulted in 9.7% and 16.2% weight loss over 20 and 28 weeks, respectively

Reduced side effects: Because the amylin component helps, patients may not need as high a dose of semaglutide, potentially lowering nausea