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Therefore, the problem that the agents successful in pre-clinical experimental autoimmune encephalitis trials, were either less effective in patients, worsened disease or caused unexpected, severe adverse events (60), may be at least partly solved with the more suited cuprizone model that reflects a toxic experimental model (12)

6.2 Endometrial polyps EP represent benign lesions characterized by focal overgrowth of the endometrium, closely associated with obesity-related microenvironmental alterations