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Circadian Rhythm Disruption as a Root Cause of DepressionCircadian clock gene variants in CLOCK, BMAL1, PER, CRY, NPAS2, and OPN4 interact with light exposure to disrupt hormones, sleep, and mood, increasing risk for depression, anxiety, and seasonal affective disorder

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Quick Answer: Patients on Zepbound should consider individualized vitamin supplementation based on dietary intake and laboratory results, typically including a standard multivitamin, with particular attention to vitamin B12, vitamin D, thiamine, and folate as needed

Step 4: Reintroduce slowly / If you choose to try the supplement again, start with a much smaller dose