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Genetics of Pancreatic -Cell Function and Insulin Secretion As discussed in the following sections, there are numerous metabolic processes and metabolites that serve to regulate pancreatic -cell insulin secretion, with glucose metabolism being the most significant

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In summary, alterations at the glutathione activator site result in an absent geometric and electrostatic complementary 3,50 for the reducing agent, explaining the inefficient reduction of numerous glutaredoxins 12,25,26,27,28,29,48 and thioredoxins by GSH