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It is proposed that the C* domain located at the C-terminus of CesAand the TE domain located at the C-terminus of CesB works as a cooperative esterification and depsipeptide elongation center, repeatedly recruiting the action of the C* domain to oligomerize tetradepsipeptides to give octa- and dodecadepsipeptides prior to macrocyclization by the TE domain

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First filing

Clinical and Aesthetic Benefits Patients and practitioners using GHK-Cu injections report a range of improvements: Smoother skin texture Increased firmness and elasticity Reduction in fine lines Improved tone and radiance Faster healing from skin damage or procedures Unlike fillers, which provide immediate but temporary volume, GHK-Cu works gradually, delivering results that develop over weeks as the skin regenerates