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Brookshire: Can also have psychiatric side effects

promotion of a tolerogenic rather than pro-inflammatory environment), T- and B cells among others, as well as their ability of expressing the enzyme 25-(OH)-D-1-hydroxylase (CYP27B1 allele), thus influencing innate and adaptive immunity, including B-cell-mediated humoral defense [108, 151, 170,171,172,173,174,175]

IVIM requires weekly monitoring, which allows for faster dose adjustments when side effects emerge or weight loss stalls

[5] Mechanistically, MOTS-c enhances glucose uptake primarily in skeletal muscle by activating key metabolic pathways such as AMPK and increasing GLUT4 expression