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NHS treatment is typically initiated and supervised by specialist weight management services, with specific duration limits (up to 2 years for semaglutide) and continuation criteria based on weight loss targets

GLP-1 specifically inhibits glucagon secretion, which is especially advantageous for individuals with type-2 diabetes (T2DM) who often have increased glucagon levels

Injections are placed into the subcutaneous fat layer not into muscle, and not so superficially that the product sits in the dermis, which increases the risk of surface irregularity

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