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Phase 2 data reported nausea (~42%), vomiting (~20%), and diarrhoea (~18%) in the highest dose cohort, consistent with the GLP-1 class
Ice crystal formation can damage the peptides structure, and each freeze-thaw cycle may reduce biological activity by 20-50%
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Across the GLP-1 receptor agonist class, including semaglutide, patients experienced an average increase of 1 to 4 beats per minute above baseline
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