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At present, it remains unclear whether these changes in PSCs contribute to the development of pancreatitis seen in patients with chronic use of GLP-1R agonists, or whether they could lead to complications of the increased PSCs proliferation due to long-term use of GLP-1 agonists

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Specific data from some events of particular interes were reported by Colombijn et al., including severe hypoglycaemia (4% in the combination group vs