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University of Oxford Study 2026 A 2026 study from the University of Oxford, tracking patients who stopped semaglutide and tirzepatide in real-world conditions, found that: People who stopped tirzepatide regained an average of 0.8 kg (approximately 1.7 lbs) per month Return to baseline weight the weight before starting treatment occurred within approximately 18 months for most patients People losing 15 kg on tirzepatide gained nearly 10 kg back within the first year after stopping Provider Perspective Karla K