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This can provide temporary fullness and a more lifted appearance

Blood 132:20042005 Baird L, Yamamoto M (2020) The Molecular mechanisms regulating the KEAP1-NRF2 pathway

Beyond engaging canonical hypothalamic and hindbrain networks that control metabolic homeostasis, GLP1RAs recruit a discrete population of Glp1r -expressing neurons in the central amygdala, which selectively suppress the consumption of palatable foods by reducing dopamine release in the nucleus accumbens

Supplements that support tirzepatide include a high-quality multivitamin (to compensate for reduced food intake), magnesium citrate (helps with constipation and sleep), omega-3 fatty acids (anti-inflammatory support), and vitamin D (often depleted in people with obesity)