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The synergistic effect of A 2A R antagonist, D 2 R agonist, and 5-HT 1A/1B R agonist also prevents L-DOPA-related dyskinesia-like behaviors

A surprising number of denials happen not because the patient doesn't qualify, but because the right information exists in their medical records and simply isn't included in the PA submission or isn't easy for the reviewer to locate

For example, sometimes people with Ehlers-Danlos syndrome respond differently to anaesthetics, or they are at an increased risk for other related conditions such as Postural Orthostatic Tachycardia Syndrome, and Mast Cell Activation Syndrome