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There are different types of PHAs, and they are much gentler, Ellis noted

Originally developed to regulate blood glucose level in patients with type 2 diabetes, these therapies have now gained significant attention for their role in weight management and broader metabolic health

Preclinical research indicates that intra-articular (IA) liraglutide attenuates synovial inflammation, decreases catabolic markers such as ADAMTS-5, and limits cartilage and bone damage across three experimental OA models, including MIA (mono-iodo-acetate), DMM (destabilization of the medial meniscus), and collagenase II-induced OA