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Centella and its constituents are classified as weak contact sensitizers and some rare cases of allergic contact dermatitis exist

Additionally, Type-IV collagen peptides located in the basal lamina, plays a pivotal role in cell adhesion due to abundance of RGD-motifs, thereby supporting the re-epithelialization process by providing a scaffold for new cell growth

Bacteriostatic water contains 0.9% benzyl alcohol as a preservative, which inhibits bacterial growth and allows safe multiple withdrawals from the same vial over time

In particular Wnt action has been shown to be involved in metabolic control via its actions in both the gut and pancreas