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doi: 10.1146/annurev.mi.46.100192.003403

An early Nature Communications study revealed that patients with symptoms of PAD that include claudication could extend their pain-free walking distance with a daily OTC supplement called nicotinamide riboside (NR, more commonly known as a form of vitamin B3.) For this study, University of Florida and Northwestern University researchers followed 90 patients with PAD throughout a six-month clinical trial

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Getting regular exercise can help improve your circulation, keeping the blood pumping to your extremities so they dont get cold