The globulin group includes transferrin and complement proteins (C3, C4, C5)
One challenge with standard berberine is poor absorptionless than 1% is typically taken up by the body

Aqua/Water/Eau, Glycerin, Cetyl Ethylhexanoate, Propanediol, Cetyl Alcohol, 3-O-Ethyl Ascorbic Acid, Niacinamide, Steareth-21, Dicaprylyl Carbonate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Ammonium Acryloyldimethyltaurate/Vp Copolymer, 1,2-Hexanediol, Synthetic Beeswax, Tetrahexyldecyl Ascorbate, Ascorbic Acid, Colloidal Gold, Polyglutamic Acid, Sodium Hyaluronate, Rubus Chamaemorus Seed Oil, Collagen, Glutathione, Tocopherol, Tocopheryl Acetate, Jojoba Esters, Riboflavin, Cyanocobalamin, Leuconostoc/Radish Root Ferment Filtrate, Cetearyl Olivate, Sorbitan Olivate, Ethylhexylglycerin, Sorbitan Isostearate, Sorbitol, Sodium Phytate, Citric Acid, Caprylyl Glycol, Dimethicone, Xanthan Gum, Polysorbate 60, Sodium Citrate, Sodium Hydroxide, Phenoxyethanol, Pentaerythrityl Tetraethylhexanoate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Mica, Tin Oxide, Parfum/Fragrance, Titanium Dioxide (Ci 77891), Iron Oxides (Ci 77491), Citral, Limonene, Linalool

In other words, someone who was overweight (a body mass index between 27 and 30) at the start of the study tended to see a similar reduction in heart disease risk as compared to someone with the highest level of obesity (a BMI over 40)