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Eli Lilly is likely considering MASLD as a separate indication for regulatory submission, which could accelerate the timeline for liver-specific approval

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Although other trials, for example the SUSTAIN 6 trial evaluating semaglutide for potential cardiovascular benefits in patients with type 2 diabetes, did not find a sex difference in the rate of reported GI events (51% more than placebo in men, 47% more than placebo in women) or in the rate of treatment discontinuation due to adverse events (76% more than placebo in men, 127% more than placebo in women)

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