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Following the initial 10-day period, researchers may consider switching to a maintenance dose of 2mg/weekly (8mg/month) as suggested by research involving long-term trials [17]

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The Model group rats were fed a rodent diet with 45% fat-derived calories for 8 consecutive weeks, followed by fasting for 1 day and intraperitoneal injection of streptozotocin (STZ) (35 mgkg)