l carnitine for subclinical hyperthyroidism Metabolite Changes during the Transition from to Euthyroidism in Patients with Graves' Disease The role of thyroid-stimulating hormone

a low ratio decreases IL-12 secretion which favors a Th2 response pattern over Th1 (a condition typically associated with chronic inflammation), while an elevated ratio favors a Th1 response (Brundu et al., 2016

The enhanced hepatic mitochondrial activity in the context of TKT deficiency has been shown to be the result of increased phospholipid synthesis, particularly increased synthesis of phosphatidylcholine which represents the major phospholipid in the mitochondrial membrane

doi:10.1021/ml300307b 61

[12] Folate supplementation may affect the course and treatment of pernicious anemia if vitamin B 12 not replaced