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Description

In general, GLP-1 is thought to have two effects, one exerted via the central nervous system and the other exerted via local receptors in the periphery

Short-acting GLP-1 agents like exenatide immediate-release (Byetta) and lixisenatide (Adlyxin) must be administered within 60 minutes before meals

See complete contraindications above

The FDA gave pharmacies and compounding facilities 60 and 90 days, respectively, from the end of each shortage to wind down operations and for patients to switch to the FDA-approved brand products that were no longer in shortage