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Management of ulcerative colitis by dichloroacetate: impact on NFATC1/NLRP3/IL1B signaling based on bioinformatics analysis combined with in vivo experimental verification

doi: 10.1016/j.animal.2020.100055 116 St-PierreN

The GPX4/GSH axis is a central regulator of ferroptosis, a form of regulated cell death (RCD) that is closely associated with lipid peroxidation

At the same time, it reduces appetite by acting on areas of the brain that control hunger, making it a dual-action drug for managing both diabetes and weight