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Nardo M, Gouda MA, Nelson BE, Barreto CMN, Slade JH, Poullard A, Zafereo ME , Hu MI, Cabanillas ME, Subbiah V

Hypertension plays a major role in the development of Cardiovascular Disease (CVD)

Dose escalation, hydration, meal size, nutrition, reflux history, other medications, and individual response can all influence tolerability

The RI data were subjected to angular transformation [sin 1 (p/ 100)], whereas in all other cases natural data were used (Armitage P.: Statistical Methods in Medical Research