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AOD-9604 Research Protocols & Administration Dosing in Published Research Research investigations have employed diverse AOD-9604 doses across species and administration routes: Rodent studies: 250-500 mcg/kg orally or intraperitoneally was most common for obesity research Rabbit models: 0.25 mg per joint for osteoarthritis studies (intra-articular injection) Pig pharmacokinetic studies: 1.5 mg/kg IV and 2 mg/kg oral for metabolism characterization Human clinical trials: Oral doses of 0.25-10 mg daily

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Pen Dosage Chart Dosage & Protocols Variations Standard Research Protocol Dose: 0.30 0.50 mg (= 1220 clicks) Duration: 30 days Frequency: Daily Cycle Interval: 10 days off before next cycle Goal / Description: Commonly used dose in weight management models