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Some people report breakouts when using whey protein supplements, though individual responses vary significantly

Pathol Int 65:210219 Kansanen E, Kuosmanen SM, Leinonen H, Levonen A-L (2013) The Keap1-Nrf2 pathway: mechanisms of activation and dysregulation in cancer

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Whilst glucagon typically raises blood glucose, early Phase 2 trial data suggest that, when combined with GLP-1 receptor activation, its net effect may include increased calorie burning and a potential reduction in liver fat, without causing clinically significant rises in blood sugar