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Description

Metalloproteins and metal sensing

Key Takeaway: The kidneys are high-energy organs that produce significant oxidative waste

TT and JH contributed equally as first authors

Additionally, pro-apoptotic proteins can be activated and anti-apoptotic proteins can be suppressed by calcitriol/VDR signaling, which may also reduce tumor-associated inflammation by suppressing the cyclooxygenase-2, prostaglandin, and NF-kB pathways