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However, most research on the relationship between periodontitis and systemic disease has not determined causality, and these diseases are largely linked by bidirectional associations

Water, Methylpropanediol, Glycerin, Niacinamide, 1,2-Hexanediol, Hydroxyacetophenone, Allantoin, Polyglyceryl-10 Laurate, Panthenol, Adenosine, Disodium EDTA, Xylitol, Arbutin, Sodium Hyaluronate, Butylene Glycol, Hydrolyzed Hyaluronic Acid , Cyanocobalamin, Gluconolactone, Ascorbyl Glucoside, Glutathione, Fragrance

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Further, targeted metabolomics results revealed that GGCT knockdown markedly attenuated TCA cycle flux, decreasing key intermediates including pyruvate, succinate and fumarate (Fig