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doi: 10.1016/j.brainresrev.2005.03.003 291 VastaR.CallegaroS.SgambetterraS.CabrasS.Di PedeF.De MatteiF.et al

In order to mimic the natural increase of SHs and their effect on GH/IGF-1 axis and skeletal growth, male patients with DSD and hypogonadism need to start testosterone therapy during pubertal age

Patel GB, Kellner ES, Clayton E, Chhiba KD, Alakija O, Bryce PJ et al (2021) Quality of life is lower in adults labeled with childhood-onset food allergy than in those with adult-onset food allergy

Although immune dysfunction is clear in ME/CFS, further studies using defined cohorts, standardised assays, and new technologies are required to determine specific patterns (488), contradicting the hypothesis that ME/CFS could be caused by a clearance failure of the pathogenic microbe (99, 107)