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These data support an inter-organ crosstalk driven by WAT lipolysis, likely through cooperative GCGR and FGF21-mediated lipolysis, adiponectin secretion and liver-derived FGF21, in favoring EE and body weight loss

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While we continue to believe that the nature of the PFS relative value system is such that all services are appropriately subject to comparisons to one another, and that codes do not necessarily need to share the same site of service, patient population, or utilization level to serve as an appropriate crosswalk, we believe that our choice of crosswalk code is a better match both in terms of total time and clinical similarity