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Description

Its mean terminal half-life after a single dose was 8.6 days and after multiple dosing was 9.3 days

Adequate hydrationcombined with gradual increases in dietary fiberhelps normalize bowel function and reduces bloating

In Phase II, the liver attaches a moleculeoften glutathioneto the toxin to make it water-soluble so it can be flushed out of the body

In the meta-analysis, SGLT2 inhibitors significantly reduced major adverse cardiovascular events (MACE), hospitalization for heart failure (HF) plus CV death, and progression of CKD by 11%, 23% and 33%, respectively, compared to placebo