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Funding The publication of this article was funded by Children's Hospital of Mexico Federico Gomez

Read more How menopause affects metabolism and how to improve yours What is metabolism, how is it affected by menopause and how can you boost yours to improve your health

We propose metabolic reprogramming-induced enhanced pathogenicity

These findings suggest that a mechanism similar to that observed in mice [10] is at work in humans and that combining metformin with DPP-4 inhibitors appears to be a rational way of enhancing GLP-1 signalling in pancreatic beta cells