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However, ROS have also useful cellular functions such as redox signaling (Collins et al., 2014

The progressive and lasting effects, driven by the new collagen production, become evident over the course of 2 to 3 months

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3.6 Increased host defense against bacterial infection Five GO:BP terms exhibited specific enrichment in proteins upregulated in CHL, including defense response to bacterium ( p adjusted = 6.8E-14) response to bacterium ( p adjusted = 2.4E-11), antimicrobial humoral response ( p adjusted = 2.1E-13), antibacterial humoral response ( p adjusted = 9.5E-10), and defense response to fungus ( p adjusted = 5.1E-10) (Supplementary Table S6)