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Conversely, animals who received NSI-189 orally for 4 weeks, following the radiation exposure, showed levels of novel environment exploration on par with control animals

Furthermore, using a murine cholangitis model, the researchers clarified the underlying mechanisms: butyrate activates peroxisome proliferator-activated receptor delta (PPARD) to promote fatty acid -oxidation (FAO)-mediated metabolic reprogramming

In that regard, the metropolitan region is particularly cited as a promising scale for ensuring resilient spatial development and dealing with the challenges of social-ecological transformation