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We also propose that augmented acute responses in this vulnerable subgroup are also accompanied by an inability to fully suppress cytokine production to below threshold levels, due to deficient antioxidant resources and low Nrf2 activity, leading to a chronic inflammatory state (Fig

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So far, bariatric surgery has proven to be the most effective approach to body weight (BW) reduction, as a recent network meta-analysis demonstrated that it was associated with a 17.7% greater BW loss compared to lifestyle intervention/medical therapy 6 , with substantial improvements or remission of T2D, dyslipidemia and hypertension 7

And that is still not all: it can also boost the antimicrobial activity of preservatives