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The fatigue associated with GLP-1 compounds appeared in retatrutide trials as well, likely related to reduced caloric intake during the adaptation phase

Complete 4-6 week protocol requires 3-9 vials depending on dose

The important clue is that free iron is not as cytotoxic as hemin, as shown by incubations with iron (FeCl 2 and FeCl 3 ) that are not toxic in culture (preliminary data at [71]) and by knowing that the structure of hemin itself contributes to its toxicity [225]