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Nevertheless, poor diet, toxins, medications, stress, and illness can deplete its levels

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developed a shikonin-loaded PLGA nanoparticle hydrogel (size not specified) that significantly downregulated p65 and p-p65 expression and reduced IL-17A, IL-17F, IL-22, IL-1, and TNF- levels in HaCaT cells and IMQ-induced mice

Human studies have linked lutein supplementation to improvements in skin tone and luminance, while another trial found that lutein supplementation improved resistance to UV-induced skin redness.50 53 Zeaxanthin (2mg) Like lutein, zeaxanthin is an antioxidant belonging to the carotenoid family