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In a clinical trial that included 183 patients with early-stage breast cancer who were to undergo treatment with taxane-based adjuvant chemotherapy, GM1 substantially reduced the occurrence of peripheral neuropathy after four cycles of chemotherapy

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The sleep deprivation rat model of mania induces hyper-locomotion, increased sleep latency, and reduced hippocampal cell proliferation, with markers of pkc overactivity such as excess phosphorylated hippocampal and prefrontal synaptosomal-associated protein 25 (SNAP-25)