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[17] While it technically refers to anemia caused specifically by autoimmune deficiency of intrinsic factor, it is commonly used to refer to B 12 -deficient anemia as a whole, regardless of cause

doi: 10.1152/physrev.00034.2006 88 HunterK.HolscherC

Your body does produce some glutathione naturally, however a poor diet, chronic stress, prescription medications and disease quickly deplete that glutathione, further increasing the inflammatory response