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Apart from the SOD1G93A transgenic animals, other models have been produced and shown to be deficient in EAAT2/GLT1 [383, 384]
Overview of the Phase 2 NEJM Trial Design and Participants The phase 2 trial was a randomised, double-blind, placebo-controlled, dose-ranging study enrolling 338 adults with obesity or overweight without type 2 diabetes, assessing retatrutide doses of 1 mg, 4 mg, 8 mg, and 12 mg over 48 weeks
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Existen varios estudios publicados al respecto de baja calidad, casos controles, retrospectivos y algn estudio aleatorizado exploratorio prueba de concepto913
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