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Critically, low doses (approximately 5x baseline levels) were effective while high doses were not, suggesting a therapeutic window

Abstract Steroidal 5-reductase is a system of NADPH dependent enzyme that catalyzes the irreversible conversion of 43-ketosteroid precursor (testosterone) to its corresponding 5-reduced metabolite (dihydrotestosterone)

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Beta-blocker meds (like metoprolol, propranolol, and glaucoma eye drops like timolol) may forestall the quick/beating heartbeat you would generally feel when your glucose falls excessively low (hypoglycemia)