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Its popularity is mostly because of the high demand for natural weight loss supplements that can mimic the effects of popular GLP-1 drugs like Ozempic (semaglutide), Wegovy, Mounjaro, and Zepbound (tirzepatide)

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[7] The relevance of these animal findings to human patients remains uncertain and is the subject of ongoing pharmacovigilance

[15] Cuando se usa con insulina o secretagogos de insulina (como sulfonilureas), puede aumentar el riesgo de hipoglucemia, lo que generalmente requiere reduccin de dosis de estos medicamentos