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While it uses different mechanisms, both peptides help answer the bigger question of how neuropeptides manage brain function in different environments

It is particularly common in individuals with certain risk factors, including those who have undergone gastric or small intestine resections, have inflammatory bowel disease, use metformin or proton pump inhibitors, follow a vegan diet, or are older than 75 years

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Could theoretical concerns about receptor downregulation, disrupting natural growth factor signaling, or other homeostasis disturbances exist