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glutathione acts as a necessary "coolant" and protector for these vital filtration units

The data were reported as mean standard deviation (SD) or median (25th and 75th percentile) for parametric and nonparametric data, respectively

Thus, ROS cause the inhibition of GAPDH activity in cells on two fronts: first, via inducing its direct oxidation and second, by causing NAD + depletion (Figure 1)