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Injection Site Rotation Why It Matters Using the same injection site repeatedly causes lipohypertrophy thickening and scarring of the subcutaneous tissue that reduces absorption consistency and eventually makes injection uncomfortable

Stress and Nervous System Regulation Vagal nerve support (breathwork, HRV biofeedback) Mind-body therapies (EFT, meditation, somatic work) 4

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*Correspondence: Hongtao Bi [email protected] Wei [email protected] Gao [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers