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Combining single-cell rna sequencing and population-based studies reveals hand osteoarthritis-associated chondrocyte subpopulations and pathways

Caturano A, Acierno C, Nevola R, et al

Microdosing means starting at a dose substantially lower than the standard starting dose and increasing it very gradually based on how your body responds

Research into metabolic decline often reveals a "NAD+ sink," where the body consumes more NAD+ than it can produce, leading to mitochondrial "misfiring" and cellular senescence